Any gene which is present as only one copy in a diploid genome, when most other genes in the genome are present as two copies. The genes on the sex chromosomes of members of the heterogametic sex of a species are all hemizygous genes (for example, in humans, males have hemizygous genes on their X and Y chromosomes because they do not have two copies of either of those chromosomes).
Selected hemizygous gene links:
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