A lab technique used to determine whether two genetic markers are linked to each other and how closely linked they are. It uses sexual reproduction which produces offspring in which the two markers may have crossed over during DNA recombination. (DNA recombination and crossing over occurs during meiosis to produce gametes in each parent). Information on the proportion of progeny which have crossed over markers is used to determine whether the markers are linked, and if so how closely.
Selected informative meiosis links:
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