The prevention of an enzyme from binding to its intended substrate as a result of the presence of another molecule which can change the shape of the enzyme, along with its active site, so that the enzyme can't bind to its intended target. The other molecule does this by binding to a part of the enzyme other than the active site. As a result, this type of enzyme inhibition cannot be reversed by increasing the amount of substrate in the reaction, as is the case with competitive inhibition.
Selected noncompetitive inhibition links:
© 1997-2006 Healthboard.com.
Healthboard.com is a purely
informational website, and should not be used as a substitute
for professional legal, medical or technical advice.