This alkaloid chemotherapy drug is a derivative of the drug camptothecin, which was originally isolated from a Chinese tree, Camptotheca acuminata but has also been found in the nothapodytes tree (Nothapodytes foetida). Topotecan is a DNA topoisomerase I inhibitor and is used to treat advanced ovarian cancer.
Selected topotecan links:
© 1997-2006 Healthboard.com.
Healthboard.com is a purely
informational website, and should not be used as a substitute
for professional legal, medical or technical advice.