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wobble hypothesis

A proposed explanation for how one transfer RNA can recognize two codons: each tRNA has an anticodon that is a base triplet, and normal base-pairing occurs between the first two bases and complimentary bases in an mRNA codon; the third base has a free play (wobble) that lets it pair with any of a number of bases that are in the third position of different codons.

Selected wobble hypothesis links:

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