CHA₂DS₂-VASc estimates the annual risk of ischaemic stroke in someone with non-valvular atrial fibrillation who is not anticoagulated. It is the score most guidelines use to decide who should be offered an oral anticoagulant. Points for age and for female sex are taken from the age and sex fields here rather than from checkboxes, so they cannot contradict each other.
- What it estimates
- Annual ischaemic stroke risk in AF
- Applies to
- Non-valvular atrial fibrillation
- Score range
- 0 to 9 points
- Original derivation
- Lip et al., Chest 2010
- Stroke rates shown
- Friberg et al., European Heart Journal 2012
Formula
CHA₂DS₂-VASc (Lip 2010, Euro Heart Survey)Score = CHF (1) + Hypertension (1) + Age ≥75 (2) or Age 65–74 (1) + Diabetes (1) + Stroke/TIA/thromboembolism (2) + Vascular disease (1) + Female sex (1)
- C
- — Congestive heart failure or LV dysfunction — 1
- H
- — Hypertension — 1
- A₂
- — Age 75 or over — 2
- D
- — Diabetes mellitus — 1
- S₂
- — Prior stroke, TIA, or thromboembolism — 2
- V
- — Vascular disease — 1
- A
- — Age 65 to 74 — 1
- Sc
- — Sex category, female — 1
Age is scored once, not twice: 2 points at 75 and over, or 1 point from 65 to 74, never both. The maximum is therefore 9, not 10. The annual stroke rates reported alongside the score are the Friberg 2012 Swedish nationwide cohort figures; the original Lip 2010 derivation cohort published different rates for the same scores, so the source is named rather than assumed.
CHA₂DS₂-VASc Calculator examples
| Input | Result | Category |
|---|---|---|
| Man, 58, no risk factors | 0 points | Anticoagulation not recommended |
| Man, 68, hypertension | 2 points | Anticoagulation recommended |
| Man, 76, hypertension and diabetes | 4 points | Anticoagulation recommended |
| Woman, 62, no risk factors | 1 point | Anticoagulation not recommended |
| Woman, 72, hypertension and diabetes | 4 points | Anticoagulation recommended |
| Man, 80, prior stroke, heart failure, vascular disease | 6 points | Anticoagulation recommended |
What is the CHA₂DS₂-VASc score?
Atrial fibrillation lets blood pool in the left atrial appendage, where it can clot and embolise to the brain. The absolute risk of that varies enormously between patients, and anticoagulation carries its own bleeding risk — so the decision to treat needs a risk estimate rather than a blanket rule.
CHA₂DS₂-VASc was published in 2010 as a refinement of the older CHADS₂ score. Its central improvement was at the low end: CHADS₂ classified a large group of patients as intermediate risk, whereas CHA₂DS₂-VASc identifies a genuinely low-risk group — men scoring 0 and women scoring 1 — in whom anticoagulation can reasonably be withheld.
It is a decision aid for starting anticoagulation. It is not a diagnostic test, it does not measure bleeding risk, and it applies to non-valvular atrial fibrillation only.
How is the score calculated?
| Component | Points |
|---|---|
| Congestive heart failure or LV dysfunction | 1 |
| Hypertension, or on treatment for it | 1 |
| Age 75 or over | 2 |
| Diabetes mellitus | 1 |
| Prior stroke, TIA, or thromboembolism | 2 |
| Vascular disease (prior MI, PAD, or aortic plaque) | 1 |
| Age 65 to 74 | 1 |
| Female sex | 1 |
| Maximum | 9 |
The two doubled items — age 75 and over, and a prior stroke or TIA — are doubled because each roughly doubles stroke risk on its own. Prior stroke is the single strongest predictor in the score, which is why anyone with one is already at or above the treatment threshold before anything else is counted.
Age is scored in one band only. Someone aged 78 scores 2 for age and nothing for the 65–74 band. This calculator derives both age and sex points from the fields above rather than offering them as checkboxes, which removes the commonest scoring error.
What does my score mean for stroke risk?
The rates below are adjusted ischaemic stroke rates per year in patients not taking an anticoagulant, from the Swedish nationwide cohort of 182,678 patients reported by Friberg and colleagues in 2012.
| Score | Stroke rate per year |
|---|---|
| 0 | 0.2% |
| 1 | 0.6% |
| 2 | 2.2% |
| 3 | 3.2% |
| 4 | 4.8% |
| 5 | 7.2% |
| 6 | 9.7% |
| 7 | 11.2% |
| 8 | 10.8% |
| 9 | 12.2% |
Two caveats are worth stating plainly. The dip at score 8 is in the source data and reflects how few patients reach the highest scores, not a transcription error. And the original Lip 2010 derivation cohort reported materially different figures for the same scores — 1.3% at score 1 rather than 0.6%, for instance — which is why any published table should say which cohort it came from.
Contemporary cohorts often report lower absolute rates than either source, because background management of hypertension, diabetes and cholesterol has improved. Treat these numbers as a well-validated ranking rather than a precise prediction for one person.
When do guidelines recommend anticoagulation?
| Score | Men | Women |
|---|---|---|
| 0 | Anticoagulation not recommended | — |
| 1 | Consider anticoagulation | Anticoagulation not recommended |
| 2 | Anticoagulation recommended | Consider anticoagulation |
| 3 or more | Anticoagulation recommended | Anticoagulation recommended |
Where anticoagulation is indicated, a direct oral anticoagulant is preferred over warfarin in non-valvular atrial fibrillation. Aspirin is not an adequate substitute — it offers little stroke protection in AF while still carrying bleeding risk, and guidelines no longer recommend it for this purpose.
The 2023 ACC/AHA/ACCP/HRS atrial fibrillation guideline moved somewhat away from treating CHA₂DS₂-VASc as a fixed threshold, framing the decision around estimated annual risk — broadly, anticoagulation where risk exceeds about 2% per year — and allowing other validated risk scores. The score remains the most widely used starting point, but it is explicitly a conversation rather than a cut-off.
Why do men and women have different thresholds?
Female sex behaves as a risk modifier rather than an independent risk factor. In a woman with no other risk factors, atrial fibrillation carries much the same stroke risk as it does in an equivalent man — but when other risk factors are present, being female amplifies their effect.
That is why a woman scoring 1 from the sex point alone is treated as low risk and not anticoagulated, while a woman scoring 2 has one genuine risk factor plus the modifier. In practice the rule is: count the score excluding the sex point, and treat the thresholds as identical from there.
Some guidelines now write the score as CHA₂DS₂-VA, dropping the sex point entirely and using one threshold for everyone, partly to avoid ambiguity for patients whose recorded sex does not reflect their situation. This calculator uses the original CHA₂DS₂-VASc definition, which is what the published stroke-rate tables were derived from.
What the score does not cover
- Bleeding risk. That needs a separate assessment — HAS-BLED and similar — and a high bleeding score is a prompt to address modifiable risk factors, not usually a reason to withhold anticoagulation.
- Valvular atrial fibrillation. Moderate-to-severe mitral stenosis and mechanical heart valves require anticoagulation with warfarin regardless of score, and direct oral anticoagulants are contraindicated in mechanical valves.
- AF burden. The score was derived in clinical AF; how it applies to brief episodes picked up by a wearable or implanted device is still an area of active study.
- Kidney function, which affects both stroke risk and the choice and dose of anticoagulant.
- Whether the patient will actually take the medication, which is often the decisive factor.
Frequently asked questions
What is a good CHA₂DS₂-VASc score?
Lower is better. A score of 0 in a man or 1 in a woman is the low-risk group in which guidelines do not recommend anticoagulation, with an adjusted stroke rate around 0.2 to 0.6% per year. Anything above that generally warrants a treatment discussion.
What is the difference between CHADS₂ and CHA₂DS₂-VASc?
CHA₂DS₂-VASc adds vascular disease, the 65 to 74 age band, and female sex, and splits age into two bands rather than one. Its main advantage is identifying a genuinely low-risk group that CHADS₂ lumped into an intermediate category, so fewer patients are anticoagulated unnecessarily.
Does a score of 1 in a woman need anticoagulation?
No. If that single point comes from female sex alone, she is in the low-risk group and guidelines do not recommend anticoagulation. Female sex acts as a risk modifier rather than a standalone risk factor, which is why the treatment threshold for women sits one point higher.
Does the score apply to paroxysmal atrial fibrillation?
Yes. Stroke risk in atrial fibrillation depends mainly on these clinical risk factors rather than on whether the rhythm is paroxysmal, persistent, or permanent. The same score and the same thresholds apply. Very brief episodes detected only by a device are a less settled question.
Can I use this score to decide about aspirin?
No. Aspirin provides little protection against stroke in atrial fibrillation while still carrying bleeding risk, and current guidelines no longer recommend it as an alternative to oral anticoagulation. The score guides whether an anticoagulant is indicated, not which antiplatelet to take.
What does 'vascular disease' mean in this score?
It means a prior myocardial infarction, peripheral artery disease, or complex aortic plaque on imaging. It does not include hypertension, which is scored separately, and most definitions exclude coronary disease found incidentally without a prior infarct or revascularisation. It is worth one point.
Sources
- Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the Euro Heart Survey on atrial fibrillation — Lip GYH et al., Chest (PubMed), 2010
- Evaluation of risk stratification schemes for ischaemic stroke and bleeding in 182 678 patients with atrial fibrillation: the Swedish Atrial Fibrillation cohort study — Friberg L, Rosenqvist M, Lip GYH, European Heart Journal (PubMed), 2012
- 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation — American College of Cardiology / American Heart Association, Circulation, 2024
- Atrial Fibrillation — What Is Atrial Fibrillation? — National Heart, Lung, and Blood Institute, 2024